Lisinopril?

Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, a family of drugs used to treat high blood pressure and some types of heart failure. Lisinopril is also used in some cases to improve survival after a heart attack.
Summary of Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
May be Beneficial: Depletion or interference—The medication may deplete or interfere with the absorption or function of the nutrient. Taking these nutrients may help replenish them. Zinc*
Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results. High-potassium foods*
Potassium supplements*
Salt substitutes*
Side effect reduction/prevention None known
Supportive interaction None known
Reduced drug absorption/bioavailability None known
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Lisinopril Interactions with Dietary Supplements
Potassium
An uncommon yet potentially serious side effect of taking ACE inhibitors is increased blood potassium levels.1 2 3 This problem is more likely to occur in people with advanced kidney disease. Taking potassium supplements,4 potassium-containing salt substitutes (No Salt®, Morton Salt Substitute®, and others),5 6 7 or large amounts of high-potassium foods at the same time as ACE inhibitors could cause life-threatening problems.8 Therefore, people should consult their healthcare practitioner before supplementing additional potassium and should have their blood levels of potassium checked periodically while taking ACE inhibitors.
Zinc
In a study of 34 people with hypertension, six months of captopril or enalapril (ACE inhibitors related to lisinopril) treatment led to decreased zinc levels in certain white blood cells,9 raising concerns about possible ACE inhibitor–induced zinc depletion.
While zinc depletion has not been reported with lisinopril, until more is known, it makes sense for people taking lisinopril long term to consider, as a precaution, taking a zinc supplement or a multimineral tablet containing zinc. (Such multiminerals usually contain no more than 99 mg of potassium, probably not enough to trigger the above-mentioned interaction.) Supplements containing zinc should also contain copper, to protect against a zinc-induced copper deficiency.
Lisinopril Interactions with Foods and Other Compounds
Food
Lisinopril may be taken with or without food.10
Medication Reviews & Side Effects for Lisinopril
Review Date: 6/10/2007
Medication: Lisinopril – – Stay Far Away
Medication Type: Generic
Length Taken: Less than 1 month
Strength: 10 mg X 1 times per day
Side Effects: Dry Mouth, Nausea, Stomach Pain, Constipation, Upset Stomach / Diarreha, Loss of Sleep, Loss of Energy, Loss of Sex Drive, Made Me Nauseous
Other Products Taken: Lexapro 40 mg
I experienced coughing at night and even during the day. Felt extremely tired, nauseated, and experienced diarreha. I’m going to be changing blood pressure medications.
Review Date: 4/10/2007
Medication: Lisinopril – – Average
Medication Type: Generic
Length Taken: Between 3 and 6 months
Strength: 20 X 1 times per day
Side Effects: High Blood Pressure, Loss of Sleep
Other Products Taken: Yes
Lisinopril causes me to have extreme coughing. At night coughing bothers my sleep, not less than two times. Taking this prescribed medication did not lower my blood pressure significantly, even after six months of taking it.
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